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Spi-1 (PU.1) 5' UTR regulatory element : ウィキペディア英語版 | Spi-1 (PU.1) 5' UTR regulatory element
The Spi-1 (PU.1) 5' UTR regulatory element is an RNA element found in the 5' UTR of Spi-1 mRNA which is able to inhibit the translation Spi-1 transcripts by 8-fold. Spi-1 regulates myeloid gene expression during haemopoietic development. Mutations in this regulatory region of the 5' UTR can lead to overexpression of Spi-1 which has been linked to development of leukaemia.〔 ==See also==
*InvR
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